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There’s a tantalizing alternative to advance the sector of neurodegenerative illnesses by creating animal fashions that precisely recapitulate key options of human pathology. In parallel, the identification and validation of translational biomarkers that assist bridge the hole between preclinical research and medical trials can speed up efforts to develop efficient remedies and therapies. That’s why Biospective has developed and extensively characterised revolutionary mouse fashions with neuropathology induced by misfolded proteins, together with amyloid-beta, tau, alpha-synuclein, and TDP-43 fashions.
On this GEN webinar, Biospective CEO & CSO Barry Bedell, MD, PhD, will talk about the multi-modality characterization of mouse fashions tailor-made for the preclinical analysis of experimental therapeutic brokers for neurodegenerative illnesses together with Alzheimer’s illness, tauopathies, Parkinson’s illness, and Amyotrophic Lateral Sclerosis (ALS). He’ll present an summary of motor, behavioral, in vivo imaging, and quantitative immunohistochemistry/multiplex immunofluorescence knowledge collected from varied fashions, together with adeno-associated virus (AAV) vector-induced, preformed fibril (PFF)-induced, and transgenic fashions.
A dwell Q&A session will observe the presentation, providing you an opportunity to pose inquiries to our skilled panelist.
